Interneurons in the spinal cord play a key role in generating the complex patterns of muscle activity that enable us to walk. These interneurons, together with motor neurons, form a neural network known as the central pattern generator (GPG). The CPG is able to function independently of the brain to generate the coordinated and rhythmic firing of motor neurons needed for walking. The Reeve Foundation has funded research to examine interneuron V3 in ways that may permit new therapies to increase locomotor network function, such as walking after spinal cord injury. Kudos, Reeve Foundation for your continuing support of people with SCI.